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Group Sequential And Adaptive Methods For Clinical Trials | C. Jennison | 2nd Edition | Taylor & Francis Group (English Medium)
|
| 10978-10978 |
The second edition of "Group Sequential And Adaptive Methods For Clinical Trials" by C. Jennison is a comprehensive guide to the latest statistical methods used in clinical trials. This book provides an in-depth exploration of group sequential and adaptive designs, which are essential tools for improving the efficiency and accuracy of clinical trials. The book begins with an introduction to the basic concepts of group sequential and adaptive designs, including their advantages and limitations. It then goes on to cover advanced topics such as interim analyses, sample size re-estimation, and adaptive randomization. Throughout the book, the author provides real-world examples and case studies to illustrate how these methods can be applied in practice. This second edition has been updated to reflect the latest developments in the field, including new regulatory guidelines and software tools. It also includes additional exercises and problems for readers to test their understanding of the material. Whether you are a researcher, statistician, or clinician involved in clinical trial design and analysis, this book will serve as an invaluable resource. With its clear explanations, practical examples, and up-to-date information, "Group Sequential And Adaptive Methods For Clinical Trials" is a must-have reference for anyone working in the field of clinical research.
Group Sequential And Adaptive Methods For Clinical Trials by C. Jennison is a highly authoritative and advanced resource that explores modern statistical methodologies used in the design and analysis of clinical trials. Published in 2026 by Taylor & Francis Group, this second edition reflects the latest developments in adaptive trial design and interim analysis, making it an essential reference for statisticians, clinical researchers, and pharmaceutical professionals.
The book provides a comprehensive treatment of group sequential methods, which allow clinical trials to be evaluated at multiple stages rather than only at completion. This approach enables early stopping for efficacy, futility, or safety, thereby improving ethical standards and resource efficiency. Alongside this, the text delves deeply into adaptive methods, which allow modifications to trial procedures based on interim results without compromising statistical validity.
Readers are guided through the theoretical foundations of these methods, including hypothesis testing, error control, and statistical inference. The book also emphasizes practical implementation, offering detailed examples, mathematical models, and real-world applications in clinical research. It explains how adaptive designs can be used to optimize sample sizes, adjust treatment allocations, and improve decision-making during ongoing trials.
A key strength of this edition is its balance between theory and application. While it rigorously covers complex statistical concepts, it also provides intuitive explanations and case studies that make the material more accessible. The book is particularly valuable for those involved in drug development, regulatory submissions, and evidence-based medicine, where efficient and flexible trial designs are increasingly important.
With 624 pages of in-depth content, this hardbound edition serves as a definitive guide for advanced learners and professionals in biostatistics and clinical research. It is suitable for postgraduate students, academic researchers, and industry experts seeking to enhance their understanding of innovative trial methodologies.
Overall, this book stands out as a critical resource for anyone involved in the planning, execution, or analysis of clinical trials, offering both the theoretical rigor and practical tools needed to implement group sequential and adaptive designs effectively.
| SKU / BOOK Code: | GSAM-9781584888475 |
| Publisher: | Taylor & Francis Group |
| Author: | Jennison C |
| Binding Type: | Hardcover |
| No. of Pages: | 624 |
| ISBN-10: | NA |
| ISBN-13: | NA |
| Edition: | 2nd |
| Language: | English Medium |
| Publish Year: | 2026-01 |
| Weight (g): | 650 |
| Product Condition: | New |
| Reading Age: | Above 18 Years |
| Country of Origin: | India |
| Genre: | Sciences, Technology & Medicine |
| Manufacturer: | Taylor & Francis Group |
| Importer: | Taylor & Francis Group |
| Packer: | Fullfilled by Supplier |
The second edition of "Group Sequential And Adaptive Methods For Clinical Trials" by C. Jennison is a comprehensive guide to the latest statistical methods used in clinical trials. This book provides an in-depth exploration of group sequential and adaptive designs, which are essential tools for improving the efficiency and accuracy of clinical trials. The book begins with an introduction to the basic concepts of group sequential and adaptive designs, including their advantages and limitations. It then goes on to cover advanced topics such as interim analyses, sample size re-estimation, and adaptive randomization. Throughout the book, the author provides real-world examples and case studies to illustrate how these methods can be applied in practice. This second edition has been updated to reflect the latest developments in the field, including new regulatory guidelines and software tools. It also includes additional exercises and problems for readers to test their understanding of the material. Whether you are a researcher, statistician, or clinician involved in clinical trial design and analysis, this book will serve as an invaluable resource. With its clear explanations, practical examples, and up-to-date information, "Group Sequential And Adaptive Methods For Clinical Trials" is a must-have reference for anyone working in the field of clinical research.
Group Sequential And Adaptive Methods For Clinical Trials by C. Jennison is a highly authoritative and advanced resource that explores modern statistical methodologies used in the design and analysis of clinical trials. Published in 2026 by Taylor & Francis Group, this second edition reflects the latest developments in adaptive trial design and interim analysis, making it an essential reference for statisticians, clinical researchers, and pharmaceutical professionals.
The book provides a comprehensive treatment of group sequential methods, which allow clinical trials to be evaluated at multiple stages rather than only at completion. This approach enables early stopping for efficacy, futility, or safety, thereby improving ethical standards and resource efficiency. Alongside this, the text delves deeply into adaptive methods, which allow modifications to trial procedures based on interim results without compromising statistical validity.
Readers are guided through the theoretical foundations of these methods, including hypothesis testing, error control, and statistical inference. The book also emphasizes practical implementation, offering detailed examples, mathematical models, and real-world applications in clinical research. It explains how adaptive designs can be used to optimize sample sizes, adjust treatment allocations, and improve decision-making during ongoing trials.
A key strength of this edition is its balance between theory and application. While it rigorously covers complex statistical concepts, it also provides intuitive explanations and case studies that make the material more accessible. The book is particularly valuable for those involved in drug development, regulatory submissions, and evidence-based medicine, where efficient and flexible trial designs are increasingly important.
With 624 pages of in-depth content, this hardbound edition serves as a definitive guide for advanced learners and professionals in biostatistics and clinical research. It is suitable for postgraduate students, academic researchers, and industry experts seeking to enhance their understanding of innovative trial methodologies.
Overall, this book stands out as a critical resource for anyone involved in the planning, execution, or analysis of clinical trials, offering both the theoretical rigor and practical tools needed to implement group sequential and adaptive designs effectively.
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